I'm a virologist. AMA

I'm a virologist. AMA.

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I've been wanting to become a virologist for a while. I always taken an interest in Viruses, especially ones like Ebola and Smallpox. How easy is it would you say, to find work as one? My backup plan is immunologist.
Also, favorite virus?

bugchasing doesn't make you a virologist, homo.

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It's pretty hard to find work as a virus nowadays, heavy competition

Doubtful

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what your salary?

pee pee in your poo poo

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why are you posting a picture of a bacteria

Do you suck cock

I want to basically research and study viruses. The Uni I'm going to doesn't have a lab AFAIK but one can hope.

Also good choices! Ebola would take my cake just because of how it interacts specifically with the immune system directly

What purpose does a virus have to exist other than to destroy life. I say this because they are not even living things, like harmful bacteria does what it does to benefit itself and the result just happens to be very negative. But a virus just exist to destroy, they aren’t alive. Why do they do what they do

which country has done the best job responding to this outbreak in your opinion.

how long is this shit going to last? by that meaning how long before we resume normalish activity.

...replicate?

Why. Bacteria has like a reason to kill people

Not OP, but basically survive. Much like how other species of bugs breed through parasitic interaction of other animals like the Tarantula Moth.

If I ate a teaspoon of raw CoV RNA would it get me?

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Can u take the vaccine for Hpv if you already have it?

the way you phrase the question implies viruses can make choices or have thoughts

viruses are just packaged data that can be taken up by actual living cells and their proteins replicate the data and package it.

But how can something survive if it’s not a living thing in the first place

H stands for hemagluttanin and N stands for neuraminidase.

Hemagluttanin is used to localize salic acid on the host cell so the virus can enter the host. Hemagluttanin has multiple isotypes but only 1-3 are infectious in humans.

Neuramidase is used by the virus to rupture the cell and escape.

These two proteins are very instrumental in paramyxoviruses and orthomyxoviruses like the flu. In fact, tamiflu targets neuraminidase and impedes it so that the viruses can't escape from the cell and thus the infection doesn't spread throughout the body.

Tell me something I don't know.

I mean benefits, retirement and only work 8 hours (plus overtime from the Coronavirus). I won't complain. It's really not a bad gig for doing what I love.

You're an idiot.

>Ebola would take my cake just because of how it interacts specifically with the immune system directly
It's so nightmarish how it attacks dendritic cells and impedes interferon so other lymphocytes can't be recruited to the site of infection.

I read this one book called Spillover by David Quammen, and this one dude who had Ebola (and survived) developed a congruent fungal infection in his throat because his immune system was just so suppressed by this thing.

If you're looking to get your foot in the door, I would recommend volunteering at a hospital and getting lab tech experience. You'd be surprised how much pipetting experience will pay off.

>I say this because they are not even living things
What makes you say that?
Parasites only exist to destroy life.
Humans only exist to leech off of nature, interfere with natural selection and pollute the earth for the sake of generating a fiat commodity with no physical or exestential value other than what we recognize it for.

>Why do they do what they do
They do what they do because they can. They can infect a host. They can hijack the host machinery to replicate. and they can kill the host.

So death is like an inadvertent result of what the virus does

Did you know viruses are embedded in your DNA from your ancestors? You can't get rid of viruses permanently.

i mean i get benefits and retirement too plus on call pay
did you have to go to grad school?

good thing we have adaptive immunity

Viruses are pussi bois

- post approved by bacterial gang 2020

Living in missoirri..not feeling so well..

why do humans replicate?
why does anything replicate to further boil in agony of existence?

OP here, I make $17 an hour after going to university for 4 years and graduate school for 2 years. I drive Uber on the weekends to help pay rent.

>kill the host.
isn't that a pitfall in their existence? kinda what humans are doing to their own environment semi-consciously?

you aint wrong though

>which country has done the best job responding to this outbreak in your opinion.
Hard to say. Probably Russia because they closed their borders ASAP.

>how long is this shit going to last? by that meaning how long before we resume normalish activity.
Who knows, man? In this day and age where people are so easily manipulated by the media where they believe things without question, it could be ages.

This

Depends on if you have anything wrong with your throat cells and their epithelia

Since SARS II is (+)ss RNA, it can be translated as soon as it gets into the host cell. So if you smoke and your epithelia is compromised and CoV RNA gets in... you might be shit out of luck.

Nope.

A vaccine is developed to prevent a disease. Once you already have it, your immune system can't be primed again for it.

Luckily for non-transformative HPV, your body can absolve you of all infection in about a year.

>viruses are just packaged data that can be taken up by actual living cells and their proteins replicate the data and package it.
Exactly.
And viruses that are too virulent have low fitness because they decrease the chance that they'll be passed on to another host.
But viruses that are not too virulent have higher fitness since they don't impede the host from contacting other people/organisms.

There has to be a balance of virulence and interactivity because too much of one or the other would be very disadvantageous and could lead to extinction of new viral lineages.

What makes you think it's not alive? It has a genome that codes for the same amino acids that all life codes for.

Depends. If a virus is too deadly, chances are it won't be passed on because it made its host too immobile to come in contact with other hosts.

Yup. Around 20% of our non-coding regions are ancestral viral genomes. How bout that?

Technically you don't have to but why wouldn't you?

>Technically you don't have to but why wouldn't you?
maybe because gradschool aint cheap and repaying school loans on $17/hr sucks

you make as much as amazon factory workers

Calling bullshit right now. Average virologist salaries are 6 figures. Go larp somewhere else

I've seen some chatter about concerns that this virus mutating into something stronger if it comes into contact specifically with bats in Brazil. Have you heard about this or was it just bullshit?

What's the deadliest virus known to man? 100% certain death more or less.

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real question here, what do you do all day?
as in whats your daily testing? RT-PCRs?

Lol your adaptive immune system doesn't go into your genome to root out viral DNA.

St. Louis Encephalitis?

Welcome to America where the hard workers still have a hard time.

Yup.

Welcome to the United States of America where the cost of living isn't only paid with money but with your energy, time, happiness, and soul.

Did I mention I kind of started out about a year ago.

Are you single?
Do you buy Starbucks coffee instead of make it at home?
Do you eat out a lot?
Do you have a girlfriend who's extremely materialistic and insecure about what her toxic friends think about her on Instagram?
Do you pay for cable/phone/internet instead of just having a cell phone with an unlimited hotspot?
Do you drive to work every day instead of take the train or ride a bike?

17/hr can be really comfortable if you know how to live within your own standards, bruh.

For now I do. I'm still kind of new to the gig and everybody starts out at rock bottom.

Nope.
Coronaviridae is very well known to undergo what is called attenuation, meaning it gets weaker and weaker with each replication and each transmission from host to host.

Also it's single-stranded genome so mutation would have to be point mutation or gene recombination.

It's really really hard for it to cross-over with another virus and mutate like how you just described naturally.

Like I said before, flu is more deadly because it can undergo what is called segment reassortment.

Instead of one strand of RNA like coronavirus, flu (Orthomyxoviridae) has I think 7 segments of genome which can cross over with other flus.

That's why swine flu was so easy to cross over into humans because of how easily it mutated.

Clearly you've never worked for a state government laboratory before.

Should I ask her out?

>17/hr can be really comfortable if you know how to live within your own standards, bruh.
cool but you get to live a much nicer life if you arent repaying unnecessary student loans for a grad school you didnt need

How soon will the covid-19 virus die out

who killed the Black Dahlia?

Depends how you define "deadly."

If you're asking about being deadly to a host, any Filovirus such as Ebola or Marburg takes the gold because those have 90% death rates.

If you mean deadly to a population... hard to say because usually the most infectious viruses aren't the most virulent and vice-versa.

I would probably say the Flu only because Spanish Flu was so unmerciful.

>real question here, what do you do all day?
A bunch of stuff. I work in a clinical lab in the immunology dept. so most of the time I'm running immunoassays on a Biorad instrument or sequencing cultured isolate via NGS.

You only miss 100% of the shots you don't take.

Well maybe if you do good in undergrad and are offered an assistantship for your grad school, you won't be in so much debt.

Hard to say. The first SARS outbreak lasted 2 years, so assuming CoVID is as similar to that strain, probably that amount of time... actually probably less because people are starting to get better.

I did.

Why do you think this virus caused such a global panic since it appears to be less deadly than the flu. I remember when the swine flu was in the news people were concerned but nowhere near the magnitude of this thing.

Is there a way to get a peach molongos fats or yes?

>Well maybe if you do good in undergrad and are offered an assistantship for your grad school, you won't be in so much debt.
i avoided it all together by getting a job straight out of college and making bank for those two extra years.

Oh yeah? Then how do I make a meme go viral?

>since it appears to be less deadly than the flu
its waaaaay more deadly than the flu
the mortality rate seems to be over 100 times greater than the flu.
and its just as contagious maybe slightly more than the flu.

>>Yup. Around 20% of our non-coding regions are ancestral viral genomes. How bout that?
That's how much waste we're lugging around, in kilograms? Can we eventually get rid of it? How much ATP is wasted to copy that trash around in an average human's life?

is this thing going to fuck up africa and south america next? with all the freaking out going on in the united states and Europe I can't imagine what's going to happen on those 2 continents.

Word.
Flu kills like .1%, maybe .2%.
Corona is anywhere from 2%-8%
Go look at mortality rates on CDC website.

what are the main enzymes involved in the influenza virus' reproduction cycle

Sometimes I whip my wiener around in circles hoping to get it going to fast enough to fly away like a helicopter?

Thank you for providing a sane voice in the noise that we all experience. I would like to post a thank you pic. Do you prefer M or F ?

>Why do you think this virus caused such a global panic since it appears to be less deadly than the flu.
The media
>I remember when the swine flu was in the news people were concerned but nowhere near the magnitude of this thing.
Because they're pissed off that they couldn't impeach Donald Trump so they tried to give him shit about this coronavirus stuff.

Well idk what to tell you.
I didn't get into virology because I thought I'd be rolling in dough. I got into it because I love it.

By uploading it onto the internet and having many people see and share it.

>That's how much waste we're lugging around, in kilograms? Can we eventually get rid of it? How much ATP is wasted to copy that trash around in an average human's life?
Just forget it man. It doesn't really decrease our fitness, but if it did, selection will act against it.

Nope. They'll be fine.

No... Flu kills up to 40% depending on the strain.

RdRp mainly in the virus and various hijacked-host enzymes that help with nucleocapsid assembly and
Other work is done by proteins.

Yes.

F.

>Just forget it man. It doesn't really decrease our fitness, but if it did, selection will act against it.
can having this junk in our DNA provide an opportunity for some genetic disorder if it mutates? basically can this shit mutate into a harmful for us outcome?