Is there any vidya protagonist who could kill/defeat the Lady of Pain (from the Planescape multiverse)?

Is there any vidya protagonist who could kill/defeat the Lady of Pain (from the Planescape multiverse)?

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>look at her and you're dead

seems unlikely

CJ and the Nerevarine

saitama

>killing the lady of pain
Shit DM detected

you didn't really understand the wiki entry you read

...

>noooooooo you can't just affect the world muh mary sue metaplot npcs are more important than you
lmao

She is the one punch man of D&D.

Could Coaxmetal fuck her up eventually?
After some time it just becomes a fight between her and the entire entropy-controlled multiverse