you mad white boi?
You mad white boi?
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Why chicken?
Nah, da fuq you keep postin dis stupid ish?
*hits blunt*
this
sciencedaily.com
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>African American men are more likely to develop prostate cancer than European American men, and are also more than twice as likely to die from it. Although there are many reasons that contribute to this health disparity, new research shows that African American men may have a distinctly different type of prostate cancer than European American men, according to new genomic fingerprinting results.
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>Racial disparities in prostate cancer are well documented with AA men having significantly higher risk of developing prostate cancer and significantly higher mortality rates than EA men. In addition, among patients presenting at the same disease stage, AA men often have higher prostate-specific antigen (PSA) levels and higher-grade tumors than EA men.
>"The number of genes expressed differently in AA and EA was a really big surprise--we found differences in over 8,000 genes," said Gattoni-Celli. "I expected something but not this massive difference and it was not a fluke.
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>Though African-American men are three times more likely to be diagnosed with a blood cancer called multiple myeloma, most scientific research on the disease has been based on people of European descent. That trend is problematic considering that African-Americans -- the most at-risk population for multiple myeloma -- have different genetics that can affect how this type of cancer progresses and what kind of targeted therapies are most effective.
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>The African American mRNA variants encode protein isoforms that make a tumor more aggressive, whereas the protein isoforms generated in European Americans appear to make the tumor less aggressive.
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>Gene mutations that lead to more aggressive colorectal cancer in African American patients discovered
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>African Americans have an incidence of CRC that is >20% higher than in whites and an even larger difference in mortality. In particular, African Americans are more often diagnosed with CRC at an earlier age and with more advanced disease; and African Americans have a greater proportion of CRCs in the proximal colon.
>It is estimated that genetic factors contribute as much as 35% to the overall risk of CRC.
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>Genetic factors in African Americans with chronic kidney disease (CKD) put them at a greater risk for end-stage renal disease (ESRD) compared to white Americans
>Both studies identified high risk genetic variants in the APOL1 gene that speed up kidney disease progression and substantially increase the risk of developing kidney failure, compared to whites and blacks with low risk variants, with or without diabetes. Approximately 1 in 10 blacks possess the high risk variants, though it is very uncommon in whites.
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>At a specified chronological age, blacks are approximately 3 years older biologically than whites. Differences in biological age between blacks and whites appear to increase up until ages 60–65 and then decline, presumably due to mortality selection. Finally, differences in biological age were found to completely account for higher levels of all-cause, cardiovascular and cancer mortality among blacks. Overall, these results suggest that being black is associated with significantly higher biological age at a given chronological age and that this is a pathway to early death both overall and from the major age-related diseases.
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>African-American women who develop gestational diabetes mellitus during pregnancy face a 52 percent increased risk of developing diabetes in the future compared to white women who develop GDM during pregnancy.
>For African American women, their risk of developing diabetes was almost 10 times greater if they had developed GDM during a past pregnancy than if they did not develop GDM.
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>The frequency of ENPP1/PC1 K121Q was higher in both African-Americans (78.5%) and Hispanics (21.9%) than in the non-Hispanic White group (13.2%). The former two groups also have a higher prevalence of type 2 diabetes (African-Americans, 14.1%, and Hispanics, 11.7%) compared to non-Hispanic Whites (6.8%). Logistic regression analysis revealed significant interactions between the ENPP1 genotype, age, and body mass index within each ethnic group.
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>Experts estimate genetic make-up accounts for roughly 40-50 percent of individuals' susceptibility to hypertension.
>A landmark study has discovered four novel gene variations associated with blood pressure in African Americans. Compared to Americans of European-ancestry, African-Americans' increased hypertension prevalence contributes to a greater risk of stroke, coronary heart disease, and end-stage renal disease.
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>Compared to Caucasian Americans, African Americans have impaired blood flow regulation in the brain that could contribute to a greater risk of cerebrovascular diseases such as stroke, transient ischaemic attack ('mini stroke'), subarachnoid haemorrhage or vascular dementia.
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>Association of polymorphisms in the promoter region of the PNMT gene with essential hypertension in African Americans but not in whites
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>African Americans have a 2- to 4-fold greater incidence of end-stage kidney disease (ESKD) than whites
>Recent advances in genetic studies have linked polymorphisms of the apolipoprotein L1 gene (APOL1) with an increased incidence of nondiabetic ESKD in African Americans, which is thought to account for ∼70% of the disparity in ESKD incidence between African Americans and whites.
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>Overexpression also was three times more frequent in blacks (15 out of 44, 34%) than in whites (13 out of 117, 11%) (p= 0.003). Recurrent disease developed in 15 out of 164 (9%) cases and was more than twice as frequent in cases when the p53 gene was overexpressed (5 out of 28, 18%) than in cases with normal expression (10 out of 136, 7%). Recurrent disease was seen in 6 out of 44 (14%) blacks compared to 9 out of 117 (8%) whites.
>These data support the hypothesis that differences in the frequency of alteration of the p53 tumor suppressor gene contribute to the racial disparity in endometrial cancer survival.
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>triple negative breast cancer more lethal in African-American women than white women or women of European descent.
>Triple negative breast cancer is an aggressive subtype of breast cancer where limited treatment is available. These tumors are the leading cause of breast cancer death in African-American women, which are usually diagnosed at an earlier age and in more advanced stages of the disease, when compared with White women.
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Young black women have a higher frequency of BRCA mutations than previously reported
Approximately 5 percent of women with breast cancer in the United States have mutations in BRCA1 or BRCA2 based on estimates in non-Hispanic white women.
They discovered that 12.4 percent of the black participants had mutations in either BRCA1 or BRCA2.
Furthermore, over 40 percent of those with a mutation had no close relatives with breast or ovarian cancer, which suggests that family history alone, may not identify those at risk for carrying a BRCA mutation.
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>Poorer outcomes for African-American women with estrogen-receptor positive breast cancer, compared with European-American patients, appears to be due, in part, to a strong survival mechanism within the cancer cells, according to a study.
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>Epidemiologists have determined that gene variations associated with breast cancer risk diverged significantly between African-American and women of European descent, a large study shows.
>Researchers have uncovered new information that may begin to explain why many African-American women are more likely to be diagnosed with aggressive, often deadly forms of breast cancer.
You’re at a restaurant and that’s sort of her job so I could care less
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>The researchers found that non-Hispanic white women were more likely to have smaller tumors, and more likely to have the less-aggressive HR+/HER2- subtype of breast cancer, compared with African-American women, who were more likely to have large tumors, more likely to have the aggressive triple-negative breast cancer, and 40 to 70 percent more likely to be diagnosed at stage 4 of all subtypes of breast cancer. Hispanic white women were 30 to 40 percent more likely to be diagnosed at stage 2 and/or stage 3 across all breast cancer subtypes.
>The disparities continued across all stages of disease. Compared with non-Hispanic whites, women of all other racial and ethnic groups were more likely to be diagnosed with more advanced stages of breast cancer, researchers found.
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>African-American women with early-stage breast cancer who have surgery to remove the cancer followed by radiation therapy have a higher chance of their cancer coming back in the breast and lymph nodes 10 years after diagnosis, compared to their Caucasian counterparts, according to the largest study of its kind.
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>African-American women had lower vitamin D levels than white women, and vitamin D deficiency was associated with a greater likelihood for aggressive breast cancer.
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>Our previous data revealed significantly higher pressure pain thresholds among individuals possessing the minor G allele of the A118G SNP of the mu-opioid receptor gene (OPRM1) compared with those with 2 consensus alleles. Moreover, ethnic differences in pain sensitivity have been widely reported.
>Few African Americans (7.4%) expressed the rare allele of OPRM1 compared to non-Hispanic whites and Hispanics (28.7% vs. 27.8%, respectively). Across the entire sample, OPRM1 genotype did not significantly affect pain sensitivity. However, analysis in each ethnic group separately revealed significant genotype effects for most pain modalities among non-Hispanic-whites (P < .05) but not Hispanics or African Americans. The G allele was associated with decreased pain sensitivity among whites only; a trend in the opposite direction emerged in Hispanics. The reasons for this dichotomy are unclear; they may involve ethnic differences in haplotypic structure, or A118G may be a tag-SNP linked to other functional polymorphisms. These findings demonstrate an ethnicity-dependent association of OPRM1 genotype with pain sensitivity.
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>G allele carriers showed lower levels of general aggression and self-reported physical aggression. Additionally, these participants exhibited increased activation in dorsolateral prefrontal, orbitofrontal, anterior cingulate and insular cortices when choosing higher punishments for the opponent. The OPRM1 polymorphism did not influence aggression in reaction to social provocation.
No, that looks delicious. I'm happy for you. Enjoy.
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>Race/ethnicity differences varied across groups and pain assessment type. Non-Hispanic white individuals were less pain-sensitive than African-American (for 21 of 34 measures), Hispanic (19 of 34), and Asian (6 of 34) individuals.
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>The study found that compared with men, women required less pressure to produce deep muscle pain and rated mechanical punctate pain as more painful. Compared with non-Hispanic white patients, black patients demonstrated greater pain sensitivity for measures of deep muscle hyperalgesia and mechanical punctate pain. Furthermore, catastrophizing partially mediated the race differences in deep muscle pain such that black participants endorsed greater pain catastrophizing, which partially accounted for their increased sensitivity to, and temporal summation of, deep muscle pain.
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>It is well established that African Americans (AA) experience greater pain associated with a variety of clinical conditions, and greater pain sensitivity to experimental pain tasks relative to non-Hispanic Whites (W). Notably, African Americans do not show the same relationships involving endogenous pain regulatory mechanisms and pain sensitivity documented in Caucasians, including positive associations between blood pressure, norepinephrine, cortisol and greater pain tolerance.
>Results.African American women demonstrated significantly lower pain tolerance across tasks compared with Whites (F1,46=6.31,p=0.0156) and also exhibited lower plasma OT levels (AA: 3.90, W: 7.05 pg/mL;p=0.0014). Greater OT levels were correlated with greater tolerance to ischemic pain (r=0.36,p=0.013) and accounted for a marginally significant portion of the ethnic difference in ischemic pain tolerance (B=+0.29,p=0.06). Greater OT was also correlated with greater tolerance of cold pressor pain (r=0.31,p=0.03); however, this association was no longer seen after the variance due to ethnicity was accounted for.
>Conclusion. These data suggest that reduced oxytocinergic function may be one of multiple biological factors contributing to the greater sensitivity to experimental ischemic pain, and to the greater burden of some types of clinical pain experienced by African Americans compared with Whites.
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>African Americans had lower tolerances for heat pain, cold pressor pain and ischemic pain compared to whites. Ratings of intensity and unpleasantness for suprathreshold heat stimuli were significantly higher among African Americans.
because it tastes delicious
Even when the power dynamics change, you seem to exhibit no class at all. Niggers are a plague
Yeah I'm mad you forgot the watermelon
Kek. Context?
If your beard hair falls in the food are you gonna say you got a pube in your food?
Black dude was blaring rap as they were praying
Lmao thread
Muslims being muslims.
>you mad white boi?
Yeah, I am not able to travel back in time to witness the hanging of Leo Frank in person.
Imagine being a haughty jew in the USA, living the good life, owning a factory, murder raping a young white girl, and you try to blame it on a black worker by manipulating another black worker.
And an all white (aka Germanic/Celtic) judge, jury and persecution actually believe the blacks over a precious jew brotherhood starlet (Leo Frank was a member of Bnai Brith) and his elite team of jewish defense attorneys.
And HANGING THE JEW INSTEAD OF THE NIGGERS!
This has blasted and roasted their anuses in such a capacity that they created the ADL of Bnai Brith, and, since it happened in 1915, been on a crusade against white and black racial cooperation.
Any black an white racial tension of the modern time is rooted in this event.
They have not forgotten, and neither should you.
Revel in it, though.
Revel in a precious jews neck snapped, hanging from a rope, all his influence worthless.
The blacks he wanted to fall succeeded him, he died, a fucking member of the yehudim was rightfully exterminated by Germanic hands in 1915.
One of the few cases of true justice in the US.
Praise this occurence daily and arm yourself with this jew slaying sword.
It cuts deep into their shriveled black hearts.
Those aren't muslims. If they are converts, they ought to be destroyed. They aren't doing the prayer correctly, so I doubt these are muzloids
You gotta be kidding me lol. The fucking idiots were on a public sidewalk and blocking the way so they can think happy thought. Go the fuck to work. If you want to pray, do it in an appropriate venue.
Can tell you're an american
it was some remembrance service and the nigger was blasting loud NIGGER music.
whyd he hit him?
what is the name of that style hat?
>shoots you in face over a piece of chicken per our people’s tradition
Flat cap.
that is a newsboy
its a newsboy, the nigger has been watching too much peaking blinders and is appropriating huwhite culture.
Take your meds, Hanz
Thanks for the info dump, user. You could have just said nigger but this is good too.
Lmao. Tay.ai's son
Lol
because the nigger is blasting music with his phone
>Take your meds, Hanz
You see, you can tell me that because I, unlike Leo Frank who got his neck snapped and his pants pissed, am alive.
HAHAHAHAHAHAHAHA
Which is great, cause I get to laugh at you AND post another lynch picture to boot.
Check out that piss stain. He sure pissed himself good.
Lol. You'd be surprised how many new people come here or don't know how valuable their genes are.
Lol based Hanz coming through
I like this energy. Don’t go to Dresden tomorrow.
I don't know why this picture of a man being served chicken like an autist prompted this, but I am thankful for the reading material.
That’s how you treat scumbags and reclaim a high trust society.
Make the niggers fearful of bad behavior.