Covid-19 had us all fooled, but now we might have finally found its secret. libertymavenstock libertymavenstock Follow Apr 4 · 8 min read
In the last 3–5 days, a mountain of anecdotal evidence has come out of NYC, Italy, Spain, etc. about COVID-19 and characteristics of patients who get seriously ill. It’s not only piling up but now leading to a general field-level consensus backed up by a few previously little-known studies that we’ve had it all wrong the whole time. Well, a few had some things eerily correct (cough Trump cough), especially with Hydroxychloroquine with Azithromicin, but we’ll get to that in a minute. There is no ‘pneumonia’ nor ARDS. At least not the ARDS with established treatment protocols and procedures we’re familiar with. Ventilators are not only the wrong solution, but high pressure intubation can actually wind up causing more damage than without, not to mention complications from tracheal scarring and ulcers given the duration of intubation often required… They may still have a use in the immediate future for patients too far to bring back with this newfound knowledge, but moving forward a new treatment protocol needs to be established so we stop treating patients for the wrong disease.
cont 1 The past 48 hours or so have seen a huge revelation: COVID-19 causes prolonged and progressive hypoxia (starving your body of oxygen) by binding to the heme groups in hemoglobin in your red blood cells. People are simply desaturating (losing o2 in their blood), and that’s what eventually leads to organ failures that kill them, not any form of ARDS or pneumonia. All the damage to the lungs you see in CT scans are from the release of oxidative iron from the hemes, this overwhelms the natural defenses against pulmonary oxidative stress and causes that nice, always-bilateral ground glass opacity in the lungs. Patients returning for re-hospitalization days or weeks after recovery suffering from apparent delayed post-hypoxic leukoencephalopathy strengthen the notion COVID-19 patients are suffering from hypoxia despite no signs of respiratory ‘tire out’ or fatigue. Here’s the breakdown of the whole process, including some ELI5-level cliff notes. Much has been simplified just to keep it digestible and layman-friendly. Your red blood cells carry oxygen from your lungs to all your organs and the rest of your body. Red blood cells can do this thanks to hemoglobin, which is a protein consisting of four “hemes”. Hemes have a special kind of iron ion, which is normally quite toxic in its free form, locked away in its center with a porphyrin acting as it’s ‘container’. In this way, the iron ion can be ‘caged’ and carried around safely by the hemoglobin, but used to bind to oxygen when it gets to your lungs.
Michael Parker
When the red blood cell gets to the alveoli, or the little sacs in your lungs where all the gas exchange happens, that special little iron ion can flip between FE2+ and FE3+ states with electron exchange and bond to some oxygen, then it goes off on its little merry way to deliver o2 elsewhere. Here’s where COVID-19 comes in. Its glycoproteins bond to the heme, and in doing so that special and toxic oxidative iron ion is “disassociated” (released). It’s basically let out of the cage and now freely roaming around on its own. This is bad for two reasons:
Tyler Wood
cont 3 1) Without the iron ion, hemoglobin can no longer bind to oxygen. Once all the hemoglobin is impaired, the red blood cell is essentially turned into a Freightliner truck cab with no trailer and no ability to store its cargo.. it is useless and just running around with COVID-19 virus attached to its porphyrin. All these useless trucks running around not delivering oxygen is what starts to lead to desaturation, or watching the patient’s spo2 levels drop. It is INCORRECT to assume traditional ARDS and in doing so, you’re treating the WRONG DISEASE. Think of it a lot like carbon monoxide poisoning, in which CO is bound to the hemoglobin, making it unable to carry oxygen. In those cases, ventilators aren’t treating the root cause; the patient’s lungs aren’t ‘tiring out’, they’re pumping just fine. The red blood cells just can’t carry o2, end of story. Only in this case, unlike CO poisoning in which eventually the CO can break off, the affected hemoglobin is permanently stripped of its ability to carry o2 because it has lost its iron ion. The body compensates for this lack of o2 carrying capacity and deliveries by having your kidneys release hormones like erythropoietin, which tell your bone marrow factories to ramp up production on new red blood cells with freshly made and fully functioning hemoglobin. This is the reason you find elevated hemoglobin and decreased blood oxygen saturation as one of the 3 primary indicators of whether the shit is about to hit the fan for a particular patient or not.
Carson Harris
cont 4 2) That little iron ion, along with millions of its friends released from other hemes, are now floating through your blood freely. As I mentioned before, this type of iron ion is highly reactive and causes oxidative damage. It turns out that this happens to a limited extent naturally in our bodies and we have cleanup & defense mechanisms to keep the balance. The lungs, in particular, have 3 primary defenses to maintain “iron homeostasis”, 2 of which are in the alveoli, those little sacs in your lungs we talked about earlier. The first of the two are little macrophages that roam around and scavenge up any free radicals like this oxidative iron. The second is a lining on the walls (called the epithelial surface) which has a thin layer of fluid packed with high levels of antioxidant molecules.. things like abscorbic acid (AKA Vitamin C) among others. Well, this is usually good enough for naturally occurring rogue iron ions but with COVID-19 running rampant your body is now basically like a progressive state letting out all the prisoners out of the prisons… it’s just too much iron and it begins to overwhelm your lungs’ countermeasures, and thus begins the process of pulmonary oxidative stress. This leads to damage and inflammation, which leads to all that nasty stuff and damage you see in CT scans of COVID-19 patient lungs. Ever noticed how it’s always bilateral? (both lungs at the same time) Pneumonia rarely ever does that, but COVID-19 does… EVERY. SINGLE. TIME.
Ryan Perez
cont 5 Once your body is now running out of control, with all your oxygen trucks running around without any freight, and tons of this toxic form of iron floating around in your bloodstream, other defenses kick in. While your lungs are busy with all this oxidative stress they can’t handle, and your organs are being starved of o2 without their constant stream of deliveries from red blood cell’s hemoglobin, and your liver is attempting to do its best to remove the iron and store it in its ‘iron vault’. Only its getting overwhelmed too. It’s starved for oxygen and fighting a losing battle from all your hemoglobin letting its iron free, and starts crying out “help, I’m taking damage!” by releasing an enzyme called alanine aminotransferase (ALT). BOOM, there is your second of 3 primary indicators of whether the shit is about to hit the fan for a particular patient or not.
Lincoln Foster
cont 6 Eventually, if the patient’s immune system doesn’t fight off the virus in time before their blood oxygen saturation drops too low, ventilator or no ventilator, organs start shutting down. No fuel, no work. The only way to even try to keep them going is max oxygen, even a hyperbaric chamber if one is available on 100% oxygen at multiple atmospheres of pressure, just to give what’s left of their functioning hemoglobin a chance to carry enough o2 to the organs and keep them alive. Yeah we don’t have nearly enough of those chambers, so some fresh red blood cells with normal hemoglobin in the form of a transfusion will have to do. The core point being, treating patients with the iron ions stripped from their hemoglobin (rendering it abnormally nonfunctional) with ventilator intubation is futile, unless you’re just hoping the patient’s immune system will work its magic in time. The root of the illness needs to be addressed. Best case scenario? Treatment regimen early, before symptoms progress too far. Hydroxychloroquine (more on that in a minute, I promise) with Azithromicin has shown fantastic, albeit critics keep mentioning ‘anecdotal’ to describe the mountain, promise and I’ll explain why it does so well next. But forget straight-up plasma with antibodies, that might work early but if the patient is too far gone they’ll need more. They’ll need all the blood: antibodies and red blood cells. No help in sending over a detachment of ammunition to a soldier already unconscious and bleeding out on the battlefield, you need to send that ammo along with some hemoglobin-stimulant-magic so that he can wake up and fire those shots at the enemy.
Joshua Perry
Dude, your graphic is mostly undecipherable gibberish (or repetitious Latin? still makes no sense).
Gavin White
cont 7 The story with Hydroxychloroquine All that hilariously misguided and counterproductive criticism the media piled on chloroquine (purely for political reasons) as a viable treatment will now go down as the biggest Fake News blunder to rule them all. The media actively engaged their activism to fight ‘bad orange man’ at the cost of thousands of lives. Shame on them. How does chloroquine work? Same way as it does for malaria. You see, malaria is this little parasite that enters the red blood cells and starts eating hemoglobin as its food source. The reason chloroquine works for malaria is the same reason it works for COVID-19 — while not fully understood, it is suspected to bind to DNA and interfere with the ability to work magic on hemoglobin. The same mechanism that stops malaria from getting its hands on hemoglobin and gobbling it up seems to do the same to COVID-19 (essentially little snippets of DNA in an envelope) from binding to it. On top of that, Hydroxychloroquine (an advanced descendant of regular old chloroquine) lowers the pH which can interfere with the replication of the virus. Again, while the full details are not known, the entire premise of this potentially ‘game changing’ treatment is to prevent hemoglobin from being interfered with, whether due to malaria or COVID-19.
Henry Green
Who the fuck is going to read that you nutcase?
Michael Johnson
cont 8 No longer can the media and armchair pseudo-physicians sit in their little ivory towers, proclaiming “DUR so stoopid, malaria is bacteria, COVID-19 is virus, anti-bacteria drug no work on virus!”. They never got the memo that a drug doesn’t need to directly act on the pathogen to be effective. Sometimes it’s enough just to stop it from doing what it does to hemoglobin, regardless of the means it uses to do so. Anyway, enough of the rant. What’s the end result here? First, the ventilator emergency needs to be re-examined. If you’re putting a patient on a ventilator because they’re going into a coma and need mechanical breathing to stay alive, okay we get it. Give ’em time for their immune systems to pull through. But if they’re conscious, alert, compliant — keep them on O2. Max it if you have to. If you HAVE to inevitably ventilate, do it at low pressure but max O2. Don’t tear up their lungs with max PEEP, you’re doing more harm to the patient because you’re treating the wrong disease. Ideally, some form of treatment needs to happen to: Inhibit viral growth and replication. Here plays CHQ+ZPAK+ZINC or other retroviral therapies being studies. Less virus, less hemoglobin losing its iron, less severity and damage.
Juan King
cont 9 Therapies used for anyone with abnormal hemoglobin or malfunctioning red blood cells. Blood transfusions. Whatever, I don’t know the full breadth and scope because I’m not a physician. But think along those lines, and treat the real disease. If you’re thinking about giving them plasma with antibodies, maybe if they’re already in bad shape think again and give them BLOOD with antibodies, or at least blood followed by plasma with antibodies. Now that we know more about how this virus works and affects our bodies, a whole range of options should open up. Don’t trust China. China is ASSHOE. (disclaimer: not talking about the people, just talking about the regime). They covered this up and have caused all kinds of death and carnage, both literal and economic. The ripples of this pandemic will be felt for decades. Fini.
Jonathan Jones
It's lorum ipsum text, a whole jumble of text used primarily as filler for web development when they are making a new site to see if the font or what have you looks good
Dominic Gray
you really expect me to read all this?
Josiah Thomas
ignore the graphic. Read cont 9 and 10 for the summary.
executive summary: 1) only use ventilators when there is absolutely no other option. they cause more harm than good. 2) max Oxygen if using ventilators with low pressure 3) Oxygenate blood via blood transfusions 4) CHQ+ZPAK+ZINC ASAP!!!
Adrian Reed
Cut in line in front of your Mom and Dad? I wouldn't think of it!
Any docs in here that can collaborate/elaborate? The key seems to be that lung damage that occurs seems to happen in both lungs which almost never happens during regular pnuemonia cases.
Joseph Baker
Not airborne AIDS but airborne Malaria
Tyler Bell
if you do get sick and they put you on a ventilator, tell the kind doc to keep the pressure low and oxygen at 100%.
Jason Lee
And your flag should be the black Isis banner. Shouldn't you be getting your women ready for dates with your moslem invaders instead of wasting time online?
Samuel Garcia
lol I was saying this in late January it’s a well known wonder drug and can treat a wide array of illnesses.
Joseph Wright
Sorry, I was educated in real books -- you may have heard of them.
And it's "moron", you illiterate tool.
Chase Nelson
BTW, get some tonic water if you can find them. Gin and tonic is good for the soul, but quinine is an effective anti-malarial.
Cameron Lee
well played Sir
Jason Moore
i read it. it seems reasonable to think this is a possibility.
personally, i still think that it's just that the fluid fills the lungs and makes it hard to take in oxygen. The respirators don't help most people because their lung muscles still work for the most part, but that most of the air sacs are gunked up.
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam, quis nostrud exercitation ullamco laboris nisi ut aliquip ex ea commodo consequat. Duis aute irure dolor in reprehenderit in voluptate velit esse cillum dolore eu fugiat nulla pariatur. Excepteur sint occaecat cupidatat non proident, sunt in culpa qui officia deserunt mollit anim id est laborum
Parker Harris
>4) CHQ+ZPAK+ZINC ASAP!!! I think 1,3 are pretty reasonable to try, but I think a lot of studies are finding that CHQ doesn't do much. Time will tell but it doesn't seem like a miracle to me.
Joseph Ramirez
my take away: 0) CHQ+ZPAK+ZINC ASAP 1) respirators on max oxygen 2) Extracorporeal membrane oxygenation (ECMO) if proper equipment 3) scheduled blood transfusions in conjunction with ECMO if possible 4) ventilators as last resort and only use min pressure and max oxygen
Hudson Morales
Good post. I'm a trained physiotherapist, it's a major cuck profession, but get this. It's much better to be upright than on your back. You need to breath deeply. You coof to get the mucus from the deep part of the lungs to the bronchial tubes, then wheeze to get it out into the back of the throat where it can be spat out. Coughing into a tissue etc provides back pressure which stops airways collapsing, and lets more mucus get out.
Then you have more surface area for gas exchange. Be sure to not stay in bed all day, stay in a chair and get up often because it helps clear the lungs.
John Roberts
remember seeing those young chinks dropping dead face first? slow oxygen deprivation seems to fit really well into the big picture. fluid in lungs not so much.
Nathaniel Rogers
Thanks for the read
Cooper Hughes
Awful cliff notes to be honest, too long. The red blood cells can't carry oxygen because of coronavirus.
Samuel Powell
Bravo!!!
I read the entire thing and IMO it makes a lot of sense!!!
Grayson Collins
Is there a way to oxyginate blood without the lungs? What do they do when doing lung surgery??
Kayden Peterson
>primarily as filler for designers who cant into thinking
I think it is called ECMO... the only reason I know this is it was mentioned in something as what to do if the ventilator doesn’t work
James Reyes
Does the virus ever unbind from the hemeglobin so it can be re-oxygenated?
Isaac Adams
read cont 4
Gabriel King
Nice post op bump
Jason Sullivan
Transfusion may be a critical step. go out and donate blood if you're not a fag
Angel Bailey
It has been a typesetting practice for many decades, it didn't come from the Internet, but periodicals.
Aiden Jones
There's also synthethic oxygen carriers.
>Perftoran, which has been rebranded as Vidaphor for marketing in North America, is an emulsion of perfluorocarbons in a surfactant and electrolyte mixture. It was developed in Russia as an oxygen-carrying intravenous plasma additive for hemorrhagic anemia and ischemic conditions from various etiologies. It was approved for clinical use in Russia in 1996 and used by the Russian Armed Forces and in civilian medical care. It was also approved in Mexico from 2005 to 2010. It has been reportedly administered to over 35,000 patients with significant evidence of benefit and relatively mild and manageable adverse effects. It may have significant potential for use in hemorrhagic shock if human red blood cells are not available, and for several other applications including treatment of vascular gas embolism, cerebral or spinal trauma, and regional ischemia.
Liam Moore
Amen.
Christopher Ward
Read all of it. Sounds really promising.
Cameron Scott
Hmm, hopefully it is safe. Maybe that is why Russia isnt having problems???
Christian Walker
pretty much if you're on ventilator, your chances are very poor.
before you get sick: vitamin c, exercise, donate blood, get an oxygen concentrator if in high risk group, stay out in the sun as much as you can (vitamin d)
if you think you're sick: lots and lots of tonic water and double your vitamin c intake. breath deeply with fresh air (ocean) and get lots of sun
if you are in a hospital: tell doc to CHQ+ZPAK+ZINC ASAP or any other anti-malarial. ask him about blood transfusions and tell him to min pressure and max O2 if you're needing ventilator.
Luis Adams
Scuba diver here, already doing my own hyberbaric oxygenation therapy. You fags aren't gonna make it.
Owen Perry
You will need to provide some good source for this part nigger or else your entire wall of text is utter garbage. There is probably a fuckton more of bullshit in your posts but nobody should bother to read this carefully until you prove the primary pivotal point.
>COVID-19 He doesn’t even get the virus is called SARS-Cov-2 and not COVID-19 that’s just the illness. I‘m not going to read stuff from anybody who doesn’t even get the basics right.
Angel Jackson
You're a kind person user Don't change
Asher Hughes
>decades Centuries, you mean
Jacob Thomas
holy shit, your argument makes much more sense. fucking noob. make a counter-argument. attacking the messenger is reddit-tier.
Jackson Morris
>The respirators don't help most people because their lung muscles still work for the most part, but that most of the air sacs are gunked up. EMT here. This is something that always surprised me.
When I was in training, they told me to give oxygen and ventilate whoever is in distress, as needed... Except people with BPCO (obstructive chronic broncho-pulmonitis). Because... Their lungs are fille with liquids and oxygen makes it worse.
Now, I can see this happening with covid-19 patients... So?
Levi Sanchez
covfefe
Carson Roberts
>nd just running around with COVID-19 virus attached to its porphyrin. All these useless trucks running around not delivering oxygen is what starts to lead to desaturation, or watching the patient’s spo2 levels drop. It is INCORRECT to assume traditional ARDS and in doing so, you’re treating the WRONG DISEASE. Think of it a lot like carbon monoxide poisoning, in which CO is bound to the hemoglobin, making it unable to carry oxygen. In those cases, ventilators aren’t treating the root cause; the patient’s lungs aren’t ‘tiring out’, they’re pumping just fine. The red blood cells just can’t carry o2, end of story. Only in this case, unlike CO poisoning in which eventually the CO can break off, the affected hemoglobin is permanently stripped of its ability to carry o2 because it has lost its iron ion. The body compensates for this lack of o2 carrying capacity and deliveries by having your kidneys release hormones like erythropoietin, which tell your bone marrow factories to ramp up production on new red blood cells with freshly made and fully
Is there a way to bind iron back to the hemoglobin?
Jackson Bailey
Go write your essays on reddit, we don't want them
Aiden Morales
Are you legitimately retarded? I asked you to provide good source for the part that I replied to. If that's the state of your reading comprehension then I don't have much hopes but I'm a nice guy so I'll give u one more chance to keep my attention.
Levi Hughes
>Is there a way to bind iron back to the hemoglobin?
No. You have to prevent it from being unbound. And we know how to do that. Hydroxycholorquine or choroquine.
We know the mechanism through which it does that. So we know both from clinical data that it works and now we also know why it works.
Thomas Garcia
lot of the lung damage is from CREATED by the ventilators. people are suffering from progressive hypoxia and the standard protocol right now is to put them on ventilators which is pretty much a death sentence right now. instead they should be focusing on delivering oxygen to the vital organs via anti-malarial and blood oxygenation mechanisms.
Ryan Lee
Changed my mind. It’s a decent hypothesis I think there was even a study or two claiming something similar. Question remains why is SaO2 okay and just breathing frequency and hearth rate rising. And many get away with that and others rapidly completely collapse in SaO2 after some time being able to compensate. Wouldn’t this theory say even in those with hearth rate rising and breathing rate rising SaO2 should already drop.
