>In-depth analysis of lipidomic profile in host cells infected with coronavirus has revealed that the LA to AA metabolism axis of those cells is the most perturbed lipidomic pathway with a concurrent increased production of AA due to both HCoV-229E and MERS-CoV infections (1). The same study showed that an exogenous supplementation of AA significantly reduced the replication of both strains indicating a potential disturbance on LA – AA axis by excess AA possibly through a feedback inhibition. Therefore, LA – AA axis is vital for the replication of this virus
science.sciencemag.org
"PA (palmitic acid) inhibited HCoV-229E replication only when supplied at high concentration"
ncbi.nlm.nih.gov
S O I B O I S B T F OOOOOOO
If this is true, tissue linoleic acid predicts vulnerability to this virus, America is well and truly fucked.
TRANSLATION
Over the past 100 years modern agriculture has become very good at producing grains in massive quantities. A byproduct of this is that we produce lots of oils from these crops and use them for cooking oils. Basedbean, Corn, Cottonseed, Etc. These oils are consumed in every food you can imagine. They are very high in Linoleic acid, which prior to the industrial processes required for the extraction of seed oils, was not consumed in high quantities. Today it can account for up to 60% of fat calories. Before 100 years ago it was generally at most 5% of fat calories unless you eat lots of olive oil, then it can be as high as 11%. Coronavirus take advantage of the metabolic cascade that results from the conversion of Linoleic acid to a more functionally valuable Arachidonic acid. The presence of significant tissue levels of Linoleic acid is prerequisite for the proliferation of the virus.
Fast food eaters and people who believe that butter is the devil and you should eat basedbean oil cuz muh cholesterol are about to get btfo.
